Term Information

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Accession
GO:0019702
Name
protein arginine N5-methyltransferase activity
Ontology
molecular_function
Synonyms
protein arginine N5-methylase activity, protein-arginine N5-methyltransferase activity, protein-arginine delta-N-methyltransferase activity, type IV PRMT activity, type IV protein arginine methyltransferase activity, S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N5-methyl-L-arginine-forming)
Alternate IDs
None
Definition
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine. Source: EC:2.1.1.322, PMID:9873020, PMID:11856739
Comment
This enzyme, characterized from the yeast Saccharomyces cerevisiae, methylates the delta-nitrogen atom of arginine residues within proteins. Among its substrates are R67 of the ribosomal protein L12.
History
See term history for GO:0019702 at QuickGO
Chem. react.
has participant hydron
has participant L-argininium residue
has participant S-adenosyl-L-methionine zwitterion
has participant N(5)-methyl-argininium(1+) residue
has participant S-adenosyl-L-homocysteine zwitterion
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0019702 from QuickGO

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Parents of protein arginine N5-methyltransferase activity (GO:0019702)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
protein arginine N5-methyltransferase activity [is_a relation] is_a  protein-arginine N-methyltransferase activity (GO:0016274)
protein arginine N5-methyltransferase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
protein arginine N5-methyltransferase activity [RO:0000057 relation] RO:0000057  L-argininium residue (CHEBI:29965)
protein arginine N5-methyltransferase activity [RO:0000057 relation] RO:0000057  S-adenosyl-L-methionine zwitterion (CHEBI:59789)
protein arginine N5-methyltransferase activity [RO:0000057 relation] RO:0000057  N(5)-methyl-argininium(1+) residue (CHEBI:88222)
protein arginine N5-methyltransferase activity [RO:0000057 relation] RO:0000057  S-adenosyl-L-homocysteine zwitterion (CHEBI:57856)

This term has no children.

EC
2.1.1.322
RHEA
48116