AmiGO 2: Term Details for "protein arginine N5-methyltransferase activity" (GO:0019702)

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Term Information

Accession: GO:0019702
Name: protein arginine N5-methyltransferase activity
Ontology: molecular_function
Synonyms: protein arginine N5-methylase activity, protein-arginine N5-methyltransferase activity, protein-arginine delta-N-methyltransferase activity, type IV PRMT activity, type IV protein arginine methyltransferase activity, S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N5-methyl-L-arginine-forming)
Alternate IDs: None
Definition: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine. Source: EC:2.1.1.322, PMID:9873020, PMID:11856739
Comment: This enzyme, characterized from the yeast Saccharomyces cerevisiae, methylates the delta-nitrogen atom of arginine residues within proteins. Among its substrates are R67 of the ribosomal protein L12.
History: See term history for GO:0019702 at QuickGO
Chem. react.: has participant N(5)-methyl-argininium(1+) residue; has participant L-argininium residue; has participant S-adenosyl-L-homocysteine zwitterion; has participant S-adenosyl-L-methionine zwitterion; has participant hydron
Subset: None
Related: Link to all genes and gene products annotated to protein arginine N5-methyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations to protein arginine N5-methyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for protein arginine N5-methyltransferase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016740 transferase activity
GO:0008168 methyltransferase activity
GO:0016741 transferase activity, transferring one-carbon groups
GO:0140096 catalytic activity, acting on a protein
GO:0008170 N-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0016273 arginine N-methyltransferase activity
GO:0008276 protein methyltransferase activity
GO:0016274 protein-arginine N-methyltransferase activity
GO:0019702 protein arginine N5-methyltransferase activity

Parents of protein arginine N5-methyltransferase activity (GO:0019702)

subject	relation	object
protein arginine N5-methyltransferase activity	RO:0000057	N(5)-methyl-argininium(1+) residue (CHEBI:88222)
protein arginine N5-methyltransferase activity	RO:0000057	L-argininium residue (CHEBI:29965)
protein arginine N5-methyltransferase activity	RO:0000057	S-adenosyl-L-homocysteine zwitterion (CHEBI:57856)
protein arginine N5-methyltransferase activity	RO:0000057	S-adenosyl-L-methionine zwitterion (CHEBI:59789)
protein arginine N5-methyltransferase activity	RO:0000057	hydron (CHEBI:15378)
protein arginine N5-methyltransferase activity	is_a	protein-arginine N-methyltransferase activity (GO:0016274)

This term has no children.

EC: 2.1.1.322
RHEA: 48116