AmiGO 2: Term Details for "protein arginine N5-methyltransferase activity" (GO:0019702)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0019702
Name: protein arginine N5-methyltransferase activity
Ontology: molecular_function
Synonyms: protein arginine N5-methylase activity, protein-arginine N5-methyltransferase activity, protein-arginine delta-N-methyltransferase activity, type IV PRMT activity, type IV protein arginine methyltransferase activity, S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N5-methyl-L-arginine-forming)
Alternate IDs: None
Definition: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine. Source: EC:2.1.1.322, PMID:9873020, PMID:11856739
Comment: This enzyme, characterized from the yeast Saccharomyces cerevisiae, methylates the delta-nitrogen atom of arginine residues within proteins. Among its substrates are R67 of the ribosomal protein L12.
History: See term history for GO:0019702 at QuickGO
Chem. react.: has participant hydron; has participant L-argininium residue; has participant S-adenosyl-L-methionine zwitterion; has participant N(5)-methyl-argininium(1+) residue; has participant S-adenosyl-L-homocysteine zwitterion
Subset: None
Related: Link to all genes and gene products annotated to protein arginine N5-methyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations to protein arginine N5-methyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for protein arginine N5-methyltransferase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016740 transferase activity
GO:0008168 methyltransferase activity
GO:0016741 transferase activity, transferring one-carbon groups
GO:0140096 catalytic activity, acting on a protein
GO:0008170 N-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0016273 arginine N-methyltransferase activity
GO:0008276 protein methyltransferase activity
GO:0016274 protein-arginine N-methyltransferase activity
GO:0019702 protein arginine N5-methyltransferase activity

Parents of protein arginine N5-methyltransferase activity (GO:0019702)

subject	relation	object
protein arginine N5-methyltransferase activity	is_a	protein-arginine N-methyltransferase activity (GO:0016274)
protein arginine N5-methyltransferase activity	RO:0000057	hydron (CHEBI:15378)
protein arginine N5-methyltransferase activity	RO:0000057	L-argininium residue (CHEBI:29965)
protein arginine N5-methyltransferase activity	RO:0000057	S-adenosyl-L-methionine zwitterion (CHEBI:59789)
protein arginine N5-methyltransferase activity	RO:0000057	N(5)-methyl-argininium(1+) residue (CHEBI:88222)
protein arginine N5-methyltransferase activity	RO:0000057	S-adenosyl-L-homocysteine zwitterion (CHEBI:57856)

This term has no children.

EC: 2.1.1.322
RHEA: 48116