Term Information

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Accession
GO:0019985
Name
translesion synthesis
Ontology
biological_process
Synonyms
bypass DNA synthesis
Alternate IDs
None
Definition
The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide. Source: GOC:vw, GOC:elh, PMID:10535901
Comment
None
History
See term history for GO:0019985 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0019985 from QuickGO

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Parents of translesion synthesis (GO:0019985)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
translesion synthesis [is_a relation] is_a  postreplication repair (GO:0006301)
translesion synthesis [is_a relation] is_a  DNA synthesis involved in DNA repair (GO:0000731)
Children of translesion synthesis (GO:0019985)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
error-free translesion synthesis (GO:0070987) [is_a relation] is_a  translesion synthesis
error-prone translesion synthesis (GO:0042276) [is_a relation] is_a  translesion synthesis
None.