Term Information

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Accession
GO:0021732
Name
midbrain-hindbrain boundary maturation
Ontology
biological_process
Synonyms
MHB maturation, isthmus maturation
Alternate IDs
None
Definition
A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. Source: GOC:cls, PMID:15541513, GOC:dph, GO_REF:0000021, GOC:dgh, GOC:jid
Comment
None
History
See term history for GO:0021732 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of midbrain-hindbrain boundary maturation (GO:0021732)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
midbrain-hindbrain boundary maturation [is_a relation] is_a  anatomical structure maturation (GO:0071695)
midbrain-hindbrain boundary maturation [RO:0002299 relation] RO:0002299  midbrain-hindbrain boundary (UBERON:0003052)
midbrain-hindbrain boundary maturation [RO:0002162 relation] RO:0002162  Vertebrata (NCBITaxon:7742)
midbrain-hindbrain boundary maturation [BFO:0000050 relation] BFO:0000050  midbrain-hindbrain boundary development (GO:0030917)
Children of midbrain-hindbrain boundary maturation (GO:0021732)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
midbrain-hindbrain boundary maturation during brain development (GO:0022004) [BFO:0000050 relation] BFO:0000050  midbrain-hindbrain boundary maturation
midbrain-hindbrain boundary maturation during neural plate development (GO:0022005) [BFO:0000050 relation] BFO:0000050  midbrain-hindbrain boundary maturation
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