AmiGO 2: Term Details for "B cell differentiation" (GO:0030183)

Accession: GO:0030183
Name: B cell differentiation
Ontology: biological_process
Synonyms: B lymphocyte differentiation, B-cell differentiation, B-lymphocyte differentiation, B cell development
Alternate IDs: GO:0042115
Definition: The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. Source: GO_REF:0000022, GOC:mah
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
History: See term history for GO:0030183 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to B cell differentiation (excluding "regulates").; Link to all direct and indirect annotations to B cell differentiation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for B cell differentiation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
B cell differentiation	is_a	B cell activation (GO:0042113)
B cell differentiation	is_a	lymphocyte differentiation (GO:0030098)
B cell differentiation	RO:0002315	B cell (CL:0000236)

subject	relation	object
mature B cell differentiation (GO:0002335)	is_a	B cell differentiation
B cell selection (GO:0002339)	BFO:0000050	B cell differentiation
positive regulation of B cell differentiation (GO:0045579)	RO:0002213	B cell differentiation
negative regulation of B cell differentiation (GO:0045578)	RO:0002212	B cell differentiation
regulation of B cell differentiation (GO:0045577)	RO:0002211	B cell differentiation
immature B cell differentiation (GO:0002327)	is_a	B cell differentiation
bursa of Fabricius (UBERON:0003903)	BFO:0000067	B cell differentiation
B cell lineage commitment (GO:0002326)	BFO:0000050	B cell differentiation

B cell differentiation