Term Information

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Accession
GO:0030343
Name
vitamin D3 25-hydroxylase activity
Ontology
molecular_function
Synonyms
cholecalciferol 25-hydroxylase activity
Alternate IDs
None
Definition
Catalysis of the reaction: vitamin D3 + NADPH + H+ + O2 = calcidiol + NADP+ + H2O. Source: ISBN:0471331309, MetaCyc:RXN-9829
Comment
None
History
See term history for GO:0030343 at QuickGO
Chem. react.
has participant calciol
has participant FMNH2(2-)
has participant calcidiol
has participant water
has participant FMN(3-)
has participant dioxygen
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of vitamin D3 25-hydroxylase activity (GO:0030343)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
vitamin D3 25-hydroxylase activity [RO:0000057 relation] RO:0000057  calciol (CHEBI:28940)
vitamin D3 25-hydroxylase activity [RO:0000057 relation] RO:0000057  FMNH2(2-) (CHEBI:57618)
vitamin D3 25-hydroxylase activity [BFO:0000050 relation] BFO:0000050  calcitriol biosynthetic process from calciol (GO:0036378)
vitamin D3 25-hydroxylase activity [RO:0000057 relation] RO:0000057  calcidiol (CHEBI:17933)
vitamin D3 25-hydroxylase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
vitamin D3 25-hydroxylase activity [RO:0000057 relation] RO:0000057  FMN(3-) (CHEBI:58210)
vitamin D3 25-hydroxylase activity [is_a relation] is_a  vitamin D 25-hydroxylase activity (GO:0070643)
vitamin D3 25-hydroxylase activity [RO:0000057 relation] RO:0000057  dioxygen (CHEBI:15379)
vitamin D3 25-hydroxylase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)

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MetaCyc
RXN-9829
Reactome
R-HSA-5602147
R-HSA-209845
RHEA
32903