AmiGO 2: Term Details for "nuclear receptor coactivator activity" (GO:0030374)

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Term Information

Accession: GO:0030374
Name: nuclear receptor coactivator activity
Ontology: molecular_function
Synonyms: ligand-activated RNA polymerase II transcription factor binding transcription factor activity, ligand-dependent nuclear receptor transcription co-activator activity, ligand-dependent nuclear receptor transcription coactivator activity, nuclear receptor transcription coactivator activity, transcription factor activity, ligand-activated RNA polymerase II transcription factor binding
Alternate IDs: GO:0038049
Definition: A transcription coactivator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator. Source: GOC:dph, GOC:tb
Comment: For usage guidance, see comment in GO:0003712 ; transcription coregulator activity.
History: See term history for GO:0030374 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to nuclear receptor coactivator activity (excluding "regulates").; Link to all direct and indirect annotations to nuclear receptor coactivator activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for nuclear receptor coactivator activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0048518 positive regulation of biological process
GO:0044238 primary metabolic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0048522 positive regulation of cellular process
GO:0009893 positive regulation of metabolic process
GO:0009889 regulation of biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0080090 regulation of primary metabolic process
GO:0009059 macromolecule biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0009891 positive regulation of biosynthetic process
GO:0031325 positive regulation of cellular metabolic process
GO:0031326 regulation of cellular biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0019219 regulation of nucleobase-containing compound metabolic process
GO:0016070 RNA metabolic process
GO:0010467 gene expression
GO:0003674 molecular_function
GO:0141187 nucleic acid biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0031328 positive regulation of cellular biosynthetic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0045935 positive regulation of nucleobase-containing compound metabolic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0051252 regulation of RNA metabolic process
GO:0032774 RNA biosynthetic process
GO:0006351 DNA-templated transcription
GO:0060090 molecular adaptor activity
GO:0010557 positive regulation of macromolecule biosynthetic process
GO:0051254 positive regulation of RNA metabolic process
GO:0010468 regulation of gene expression
GO:2001141 regulation of RNA biosynthetic process
GO:1902680 positive regulation of RNA biosynthetic process
GO:0030674 protein-macromolecule adaptor activity
GO:0006355 regulation of DNA-templated transcription
GO:0140110 transcription regulator activity
GO:0045893 positive regulation of DNA-templated transcription
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0030374 nuclear receptor coactivator activity

Parents of nuclear receptor coactivator activity (GO:0030374)

subject	relation	object
nuclear receptor coactivator activity	is_a	transcription coactivator activity (GO:0003713)

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