AmiGO 2: Term Details for "formimidoyltetrahydrofolate cyclodeaminase activity" (GO:0030412)

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Term Information

Accession: GO:0030412
Name: formimidoyltetrahydrofolate cyclodeaminase activity
Ontology: molecular_function
Synonyms: 5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing), 5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing; 5,10-methenyltetrahydrofolate-forming), formiminotetrahydrofolate cyclodeaminase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H+ = 5,10-methenyltetrahydrofolate + NH4. Source: RHEA:22736, EC:4.3.1.4
Comment: Note that cyclodeaminases are lyases according to EC, whereas deaminases are hydrolases.
History: See term history for GO:0030412 at QuickGO
Chem. react.: has participant ammonium; has participant hydron; has participant (6R)-5,10-methenyltetrahydrofolate; has participant 5-formimidoyltetrahydrofolate(2-)
Subset: None
Related: Link to all genes and gene products annotated to formimidoyltetrahydrofolate cyclodeaminase activity (excluding "regulates").; Link to all direct and indirect annotations to formimidoyltetrahydrofolate cyclodeaminase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for formimidoyltetrahydrofolate cyclodeaminase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016840 carbon-nitrogen lyase activity
GO:0016841 ammonia-lyase activity
GO:0030412 formimidoyltetrahydrofolate cyclodeaminase activity

Parents of formimidoyltetrahydrofolate cyclodeaminase activity (GO:0030412)

subject	relation	object
formimidoyltetrahydrofolate cyclodeaminase activity	RO:0000057	ammonium (CHEBI:28938)
formimidoyltetrahydrofolate cyclodeaminase activity	is_a	ammonia-lyase activity (GO:0016841)
formimidoyltetrahydrofolate cyclodeaminase activity	RO:0000057	hydron (CHEBI:15378)
formimidoyltetrahydrofolate cyclodeaminase activity	RO:0000057	(6R)-5,10-methenyltetrahydrofolate (CHEBI:57455)
formimidoyltetrahydrofolate cyclodeaminase activity	RO:0000057	5-formimidoyltetrahydrofolate(2-) (CHEBI:57456)

This term has no children.

EC: 4.3.1.4
KEGG_REACTION: R02302
MetaCyc: 4.3.1.4-RXN
Reactome: R-HSA-70920
RHEA: 22736