Term Information

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Accession
GO:0030906
Name
retromer, cargo-selective complex
Ontology
cellular_component
Synonyms
cargo-selective retromer subcomplex, retromer CSC, retromer complex, inner shell, retromer, CRC, retromer, cargo recognition complex
Alternate IDs
None
Definition
The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals. Source: GOC:bf, PMID:9700157, PMID:11102511, PMID:26220253
Comment
None
History
See term history for GO:0030906 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of retromer, cargo-selective complex (GO:0030906)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
retromer, cargo-selective complex [BFO:0000050 relation] BFO:0000050  retromer complex (GO:0030904)
retromer, cargo-selective complex [is_a relation] is_a  membrane protein complex (GO:0098796)
retromer, cargo-selective complex [RO:0002162 relation] RO:0002162  cellular organisms (NCBITaxon:131567)

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None.