AmiGO 2: Term Details for "programmed DNA elimination by chromosome breakage" (GO:0031052)

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Term Information

Accession: GO:0031052
Name: programmed DNA elimination by chromosome breakage
Ontology: biological_process
Synonyms: chromosome breakage
Alternate IDs: None
Definition: Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage. Source: PMID:32165395, PMID:15956677, GOC:ns, PMID:25303953
Comment: Note that this term refers to breakage of chromosomes during normal DNA well characterized in ciliates but also present in many vertebrates; it is not to be used for DNA damage or other abnormal occurrences.
History: See term history for GO:0031052 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to programmed DNA elimination by chromosome breakage (excluding "regulates").; Link to all direct and indirect annotations to programmed DNA elimination by chromosome breakage (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for programmed DNA elimination by chromosome breakage (excluding "regulates").

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0008152 metabolic process
GO:0048519 negative regulation of biological process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0048523 negative regulation of cellular process
GO:0009892 negative regulation of metabolic process
GO:0071704 organic substance metabolic process
GO:0009889 regulation of biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0009059 macromolecule biosynthetic process
GO:0009890 negative regulation of biosynthetic process
GO:0031324 negative regulation of cellular metabolic process
GO:1901576 organic substance biosynthetic process
GO:0031326 regulation of cellular biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0010467 gene expression
GO:0031327 negative regulation of cellular biosynthetic process
GO:0010605 negative regulation of macromolecule metabolic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0010558 negative regulation of macromolecule biosynthetic process
GO:0010468 regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0031049 programmed DNA elimination
GO:0031052 programmed DNA elimination by chromosome breakage

Parents of programmed DNA elimination by chromosome breakage (GO:0031052)

subject	relation	object
programmed DNA elimination by chromosome breakage	is_a	programmed DNA elimination (GO:0031049)

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