Term Information

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Accession
GO:0031080
Name
nuclear pore outer ring
Ontology
cellular_component
Synonyms
Nup107-120 complex, Nup107-160 complex, Nup84 complex
Alternate IDs
None
Definition
A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates). Source: PMID:18046406, GOC:dgf, PMID:19524430, PMID:20947011, PMID:22419078
Comment
None
History
See term history for GO:0031080 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of nuclear pore outer ring (GO:0031080)
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nuclear pore outer ring [is_a relation] is_a  nuclear protein-containing complex (GO:0140513)
nuclear pore outer ring [BFO:0000050 relation] BFO:0000050  nuclear pore (GO:0005643)

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