AmiGO 2: Term Details for "platelet alpha granule" (GO:0031091)

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Term Information

Accession: GO:0031091
Name: platelet alpha granule
Ontology: cellular_component
Synonyms: platelet alpha-granule
Alternate IDs: None
Definition: A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG). Source: PMID:8467233
Comment: None
History: See term history for GO:0031091 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to platelet alpha granule (excluding "regulates").; Link to all direct and indirect annotations to platelet alpha granule (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for platelet alpha granule (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
CARO:0030000 biological entity
GO:0110165 cellular anatomical entity
GO:0016043 cellular component organization
GO:0071840 cellular component organization or biogenesis
GO:0051179 localization
CARO:0000000 anatomical entity
GO:0065007 biological regulation
GO:0051234 establishment of localization
GO:0005622 intracellular anatomical structure
GO:0061024 membrane organization
GO:0043226 organelle
GO:0006996 organelle organization
UBERON:0001062 anatomical entity
CL:0000000 cell
GO:0043229 intracellular organelle
CARO:0000006 material anatomical entity
GO:0061025 membrane fusion
GO:0043227 membrane-bounded organelle
GO:0032501 multicellular organismal process
GO:0048284 organelle fusion
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0032940 secretion by cell
GO:0006810 transport
GO:0016192 vesicle-mediated transport
GO:0007154 cell communication
CARO:0000003 connected anatomical structure
GO:0006887 exocytosis
GO:0140352 export from cell
GO:0043231 intracellular membrane-bounded organelle
UBERON:0000465 material anatomical entity
GO:0071705 nitrogen compound transport
GO:0090174 organelle membrane fusion
GO:0071702 organic substance transport
GO:0065008 regulation of biological quality
GO:0006950 response to stress
GO:0046903 secretion
GO:0023052 signaling
GO:0003008 system process
GO:0031982 vesicle
GO:0016050 vesicle organization
UBERON:0000061 anatomical structure
GO:0007267 cell-cell signaling
GO:0005575 cellular_component
GO:0003013 circulatory system process
GO:0005737 cytoplasm
GO:0140029 exocytic process
GO:0097708 intracellular vesicle
GO:0015844 monoamine transport
GO:0015850 organic hydroxy compound transport
GO:0050878 regulation of body fluid levels
GO:0009611 response to wounding
CL:0000151 secretory cell
GO:0006906 vesicle fusion
CL:0000457 biogenic amine secreting cell
GO:0008015 blood circulation
GO:0050817 coagulation
GO:0031410 cytoplasmic vesicle
CL:0000988 hematopoietic cell
GO:0007599 hemostasis
GO:0001820 serotonin secretion
GO:0006837 serotonin transport
GO:0023061 signal release
GO:0099500 vesicle fusion to plasma membrane
GO:0042060 wound healing
CL:0000225 anucleate cell
CL:0000081 blood cell
GO:0007596 blood coagulation
GO:0012505 endomembrane system
CL:0000763 myeloid cell
GO:0099503 secretory vesicle
CL:0000458 serotonin secreting cell
CL:0000233 platelet
GO:0030141 secretory granule
GO:0031091 platelet alpha granule
GO:0031093 platelet alpha granule lumen
GO:0031092 platelet alpha granule membrane

Parents of platelet alpha granule (GO:0031091)

subject	relation	object
platelet alpha granule	is_a	secretory granule (GO:0030141)
platelet alpha granule	BFO:0000050	platelet (CL:0000233)
platelet alpha granule	RO:0002162	Eumetazoa (NCBITaxon:6072)

Children of platelet alpha granule (GO:0031091)

subject	relation	object
platelet alpha granule membrane (GO:0031092)	RO:0002007	platelet alpha granule
platelet alpha granule organization (GO:0070889)	RO:0002592	platelet alpha granule
platelet alpha granule lumen (GO:0031093)	BFO:0000050	platelet alpha granule

Wikipedia: Platelet_alpha-granule