AmiGO 2: Term Details for "DNA replication preinitiation complex" (GO:0031261)

Accession: GO:0031261
Name: DNA replication preinitiation complex
Ontology: cellular_component
Synonyms: pre-IC
Alternate IDs: None
Definition: A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present. Source: GOC:rb, GOC:jl, GOC:pr, GOC:vw, GOC:bf, GOC:hjd, PMID:15194812, PMID:17230184, PMID:12694535
Comment: None
History: See term history for GO:0031261 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to DNA replication preinitiation complex (excluding "regulates").; Link to all direct and indirect annotations to DNA replication preinitiation complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for DNA replication preinitiation complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
DNA replication preinitiation complex	is_a	protein-DNA complex (GO:0032993)
DNA replication preinitiation complex	BFO:0000051	nuclear pre-replicative complex (GO:0005656)
DNA replication preinitiation complex	BFO:0000050	nucleoplasm (GO:0005654)
DNA replication preinitiation complex	is_a	nuclear protein-containing complex (GO:0140513)

subject	relation	object
DNA replication preinitiation complex assembly (GO:0071163)	RO:0002588	DNA replication preinitiation complex
GINS complex (GO:0000811)	is_a	DNA replication preinitiation complex
CMG complex (GO:0071162)	is_a	DNA replication preinitiation complex

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