AmiGO 2: Term Details for "response to methotrexate" (GO:0031427)

Accession: GO:0031427
Name: response to methotrexate
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase. Source: ISBN:0198506732, GOC:ef, GOC:mah
Comment: None
History: See term history for GO:0031427 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to response to methotrexate (excluding "regulates").; Link to all direct and indirect annotations to response to methotrexate (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for response to methotrexate (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
response to methotrexate	RO:0004009	methotrexate(2-) (CHEBI:50681)
response to methotrexate	is_a	response to organic cyclic compound (GO:0014070)
response to methotrexate	is_a	response to oxygen-containing compound (GO:1901700)
response to methotrexate	is_a	response to organonitrogen compound (GO:0010243)

subject	relation	object
cellular response to methotrexate (GO:0071414)	is_a	response to methotrexate

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