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peptidyl-proline 4-dioxygenase activity

Term Information

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Accession
GO:0031545
Name
peptidyl-proline 4-dioxygenase activity
Ontology
molecular_function
Synonyms
HIF-type prolyl 4-hydroxylase, prolyl 4-hydroxylase
Alternate IDs
None
Definition
Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2. Source: GOC:mah
Comment
None
History
See term history for GO:0031545 at QuickGO
Chem. react.
has participant 2-oxoglutarate(2-)
has participant carbon dioxide
has participant dioxygen
has participant trans-4-hydroxy-L-proline residue
has participant succinate(2-)
has participant L-proline residue
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0031545 from QuickGO

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Parents of peptidyl-proline 4-dioxygenase activity (GO:0031545)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
peptidyl-proline 4-dioxygenase activity [RO:0000057 relation] RO:0000057  2-oxoglutarate(2-) (CHEBI:16810)
peptidyl-proline 4-dioxygenase activity [RO:0000057 relation] RO:0000057  carbon dioxide (CHEBI:16526)
peptidyl-proline 4-dioxygenase activity [RO:0000057 relation] RO:0000057  dioxygen (CHEBI:15379)
peptidyl-proline 4-dioxygenase activity [RO:0000057 relation] RO:0000057  trans-4-hydroxy-L-proline residue (CHEBI:61965)
peptidyl-proline 4-dioxygenase activity [RO:0000057 relation] RO:0000057  succinate(2-) (CHEBI:30031)
peptidyl-proline 4-dioxygenase activity [RO:0000057 relation] RO:0000057  L-proline residue (CHEBI:50342)
peptidyl-proline 4-dioxygenase activity [is_a relation] is_a  peptidyl-proline dioxygenase activity (GO:0031543)
Children of peptidyl-proline 4-dioxygenase activity (GO:0031545)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
hypoxia-inducible factor-proline dioxygenase activity (GO:0160082) [is_a relation] is_a  peptidyl-proline 4-dioxygenase activity
procollagen-proline 4-dioxygenase activity (GO:0004656) [is_a relation] is_a  peptidyl-proline 4-dioxygenase activity