AmiGO 2: Term Details for "receptor internalization" (GO:0031623)

Accession: GO:0031623
Name: receptor internalization
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane. Source: GOC:signaling, PMID:19643732, GOC:bf, GOC:mah, PMID:15006537
Comment: None
History: See term history for GO:0031623 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to receptor internalization (excluding "regulates").; Link to all direct and indirect annotations to receptor internalization (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for receptor internalization (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
receptor internalization	is_a	receptor-mediated endocytosis (GO:0006898)

subject	relation	object
regulation of receptor internalization (GO:0002090)	RO:0002211	receptor internalization
regulation of signal transduction by receptor internalization (GO:0038009)	is_a	receptor internalization
positive regulation of receptor internalization (GO:0002092)	RO:0002213	receptor internalization
G protein-coupled receptor internalization (GO:0002031)	is_a	receptor internalization
neurotransmitter receptor internalization (GO:0099590)	is_a	receptor internalization
Wnt receptor internalization (GO:0038017)	is_a	receptor internalization
negative regulation of receptor internalization (GO:0002091)	RO:0002212	receptor internalization
B cell receptor internalization (GO:0036300)	is_a	receptor internalization
receptor internalization involved in canonical Wnt signaling pathway (GO:2000286)	is_a	receptor internalization
insulin receptor internalization (GO:0038016)	is_a	receptor internalization

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