AmiGO 2: Term Details for "plasminogen activation" (GO:0031639)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0031639
Name: plasminogen activation
Ontology: biological_process
Synonyms: cleavage of plasminogen to plasmin
Alternate IDs: None
Definition: The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide. Source: PMID:9548733
Comment: None
History: See term history for GO:0031639 at QuickGO
Chem. react.: None
Subset: goslim_chembl
Related: Link to all genes and gene products annotated to plasminogen activation (excluding "regulates").; Link to all direct and indirect annotations to plasminogen activation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for plasminogen activation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0071704 organic substance metabolic process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:1901576 organic substance biosynthetic process
GO:0009059 macromolecule biosynthetic process
GO:1901564 organonitrogen compound metabolic process
GO:0044238 primary metabolic process
GO:0010467 gene expression
GO:0019538 protein metabolic process
GO:0051604 protein maturation
GO:0006508 proteolysis
GO:0016485 protein processing
GO:0031638 zymogen activation
GO:0031639 plasminogen activation
GO:0010757 negative regulation of plasminogen activation
GO:0010756 positive regulation of plasminogen activation
GO:0010755 regulation of plasminogen activation

Parents of plasminogen activation (GO:0031639)

subject	relation	object
plasminogen activation	is_a	zymogen activation (GO:0031638)

Children of plasminogen activation (GO:0031639)

subject	relation	object
positive regulation of plasminogen activation (GO:0010756)	RO:0002213	plasminogen activation
negative regulation of plasminogen activation (GO:0010757)	RO:0002212	plasminogen activation
regulation of plasminogen activation (GO:0010755)	RO:0002211	plasminogen activation

GONUTS Add usage comments for this term on the GONUTS wiki.