Term Information

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Accession
GO:0031955
Name
short-chain fatty acid-CoA ligase activity
Ontology
molecular_function
Synonyms
short-chain fatty-acid-CoA ligase activity, short-chain-fatty-acid-CoA ligase activity, short-chain fatty acid activation
Alternate IDs
None
Definition
Catalysis of the reaction: a short-chain fatty acid + ATP + CoA = a short-chain fatty acyl-CoA + AMP + diphosphate. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. Source: PMID:34904027, RHEA:52860
Comment
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
History
See term history for GO:0031955 at QuickGO
Chem. react.
has participant diphosphate(3-)
has participant coenzyme A(4-)
has participant short-chain fatty acid anion
has participant ATP(4-)
has participant short chain fatty acyl-CoA(4-)
has participant adenosine 5'-monophosphate(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of short-chain fatty acid-CoA ligase activity (GO:0031955)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
short-chain fatty acid-CoA ligase activity [is_a relation] is_a  CoA-ligase activity (GO:0016405)
short-chain fatty acid-CoA ligase activity [is_a relation] is_a  fatty acid ligase activity (GO:0015645)
short-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  diphosphate(3-) (CHEBI:33019)
short-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  coenzyme A(4-) (CHEBI:57287)
short-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  short-chain fatty acid anion (CHEBI:58951)
short-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  ATP(4-) (CHEBI:30616)
short-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  short chain fatty acyl-CoA(4-) (CHEBI:137040)
short-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  adenosine 5'-monophosphate(2-) (CHEBI:456215)
Children of short-chain fatty acid-CoA ligase activity (GO:0031955)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
propionate-CoA ligase activity (GO:0050218) [is_a relation] is_a  short-chain fatty acid-CoA ligase activity
2-methylbutanoate-CoA ligase activity (GO:0043759) [is_a relation] is_a  short-chain fatty acid-CoA ligase activity
RHEA
52860