Term Information

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Accession
GO:0031956
Name
medium-chain fatty acid-CoA ligase activity
Ontology
molecular_function
Synonyms
medium-chain fatty-acid-CoA ligase activity, medium-chain-fatty-acid-CoA ligase activity, medium-chain fatty acid activation
Alternate IDs
None
Definition
Catalysis of the reaction: a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons. Source: RHEA:48340
Comment
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
History
See term history for GO:0031956 at QuickGO
Chem. react.
has participant adenosine 5'-monophosphate(2-)
has participant diphosphate(3-)
has participant medium-chain fatty acid anion
has participant coenzyme A(4-)
has participant ATP(4-)
has participant medium-chain fatty acyl-CoA(4-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of medium-chain fatty acid-CoA ligase activity (GO:0031956)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
medium-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  adenosine 5'-monophosphate(2-) (CHEBI:456215)
medium-chain fatty acid-CoA ligase activity [is_a relation] is_a  fatty acid ligase activity (GO:0015645)
medium-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  diphosphate(3-) (CHEBI:33019)
medium-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  medium-chain fatty acid anion (CHEBI:59558)
medium-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  coenzyme A(4-) (CHEBI:57287)
medium-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  ATP(4-) (CHEBI:30616)
medium-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  medium-chain fatty acyl-CoA(4-) (CHEBI:90546)
medium-chain fatty acid-CoA ligase activity [is_a relation] is_a  CoA-ligase activity (GO:0016405)
Children of medium-chain fatty acid-CoA ligase activity (GO:0031956)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
decanoate-CoA ligase activity (GO:0102391) [is_a relation] is_a  medium-chain fatty acid-CoA ligase activity
EC
6.2.1.2
RHEA
48340