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Accession
GO:0031957
Name
very long-chain fatty acid-CoA ligase activity
Ontology
molecular_function
Synonyms
very-long-chain fatty acid-CoA ligase activity, very-long-chain-fatty-acid-CoA ligase activity, very-long-chain fatty acid activation
Alternate IDs
None
Definition
Catalysis of the reaction: a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. Source: PMID:18024425, RHEA:54536
Comment
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
History
See term history for GO:0031957 at QuickGO
Chem. react.
has participant coenzyme A(4-)
has participant very long-chain fatty acyl-CoA(4-)
has participant ATP(4-)
has participant adenosine 5'-monophosphate(2-)
has participant diphosphate(3-)
has participant very long-chain fatty acid anion
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of very long-chain fatty acid-CoA ligase activity (GO:0031957)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
very long-chain fatty acid-CoA ligase activity [is_a relation] is_a  fatty acid ligase activity (GO:0015645)
very long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  coenzyme A(4-) (CHEBI:57287)
very long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  very long-chain fatty acyl-CoA(4-) (CHEBI:138261)
very long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  ATP(4-) (CHEBI:30616)
very long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  adenosine 5'-monophosphate(2-) (CHEBI:456215)
very long-chain fatty acid-CoA ligase activity [is_a relation] is_a  CoA-ligase activity (GO:0016405)
very long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  diphosphate(3-) (CHEBI:33019)
very long-chain fatty acid-CoA ligase activity [RO:0000057 relation] RO:0000057  very long-chain fatty acid anion (CHEBI:58950)

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