AmiGO 2: Term Details for "DSIF complex" (GO:0032044)

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Term Information

Accession: GO:0032044
Name: DSIF complex
Ontology: cellular_component
Synonyms: 5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole sensitivity inducing factor complex, DRB sensitivity inducing factor complex, Spt4-Spt5 complex, Spt5-Spt4 complex
Alternate IDs: None
Definition: A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes. Source: PMID:12676794, PMID:16581788, PMID:19460865, PMID:12242279, PMID:12653964
Comment: None
History: See term history for GO:0032044 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to DSIF complex (excluding "regulates").; Link to all direct and indirect annotations to DSIF complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for DSIF complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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UBERON:0000061 anatomical structure
CARO:0030000 biological entity
CARO:0000000 anatomical entity
CL:0000000 cell
GO:0110165 cellular anatomical entity
UBERON:0001062 anatomical entity
GO:0005622 intracellular anatomical structure
CARO:0000006 material anatomical entity
GO:0031974 membrane-enclosed lumen
GO:0043226 organelle
CARO:0000003 connected anatomical structure
GO:0043229 intracellular organelle
UBERON:0000465 material anatomical entity
GO:0043227 membrane-bounded organelle
GO:0043233 organelle lumen
GO:0005575 cellular_component
GO:0043231 intracellular membrane-bounded organelle
GO:0070013 intracellular organelle lumen
GO:0005634 nucleus
PR:000050567 protein-containing material entity
GO:0031981 nuclear lumen
GO:0032991 protein-containing complex
GO:0140513 nuclear protein-containing complex
GO:0005654 nucleoplasm
GO:0008023 transcription elongation factor complex
GO:0032044 DSIF complex

Parents of DSIF complex (GO:0032044)

subject	relation	object
DSIF complex	is_a	transcription elongation factor complex (GO:0008023)

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