AmiGO 2: Term Details for "DNA duplex unwinding" (GO:0032508)

Accession: GO:0032508
Name: DNA duplex unwinding
Ontology: biological_process
Synonyms: DNA unwinding, duplex DNA melting
Alternate IDs: None
Definition: The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands. Source: GOC:isa_complete, GOC:mah
Comment: Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.
History: See term history for GO:0032508 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to DNA duplex unwinding (excluding "regulates").; Link to all direct and indirect annotations to DNA duplex unwinding (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for DNA duplex unwinding (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
DNA duplex unwinding	is_a	DNA geometric change (GO:0032392)

subject	relation	object
DNA helicase activity (GO:0003678)	BFO:0000050	DNA duplex unwinding
positive regulation of DNA duplex unwinding (GO:1905464)	RO:0002213	DNA duplex unwinding
regulation of DNA duplex unwinding (GO:1905462)	RO:0002211	DNA duplex unwinding
negative regulation of DNA duplex unwinding (GO:1905463)	RO:0002212	DNA duplex unwinding
nucleotide-excision repair, DNA duplex unwinding (GO:0000717)	is_a	DNA duplex unwinding
DNA unwinding involved in DNA replication (GO:0006268)	is_a	DNA duplex unwinding

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