AmiGO 2: Term Details for "sulfiredoxin activity" (GO:0032542)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0032542
Name: sulfiredoxin activity
Ontology: molecular_function
Synonyms: peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase activity, sulphiredoxin activity, Srx1, peroxiredoxin-(S-hydroxy-S-oxocysteine):thiol oxidoreductase [ATP-hydrolysing; peroxiredoxin-(S-hydroxycysteine)-forming]
Alternate IDs: None
Definition: Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R. Source: PMID:16102934, EC:1.8.98.2
Comment: None
History: See term history for GO:0032542 at QuickGO
Chem. react.: has participant ADP(3-); has participant 3-sulfino-L-alanine(1-) residue; has participant L-cystine residue; has participant S-hydroxy-L-cysteine residue; has participant ATP(4-); has participant hydrogenphosphate; has participant L-cysteine residue
Subset: None
Related: Link to all genes and gene products annotated to sulfiredoxin activity (excluding "regulates").; Link to all direct and indirect annotations to sulfiredoxin activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for sulfiredoxin activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

CARO:0030000 biological entity
CARO:0000000 anatomical entity
GO:0008150 biological_process
UBERON:0001062 anatomical entity
GO:0009987 cellular process
CARO:0000006 material anatomical entity
GO:0050896 response to stimulus
GO:0051716 cellular response to stimulus
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0042221 response to chemical
UBERON:0000061 anatomical structure
GO:0070887 cellular response to chemical stimulus
GO:0009636 response to toxic substance
CL:0000000 cell
GO:0097237 cellular response to toxic substance
GO:0098754 detoxification
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:1990748 cellular detoxification
GO:0098869 cellular oxidant detoxification
GO:0016491 oxidoreductase activity
GO:0016209 antioxidant activity
GO:0016667 oxidoreductase activity, acting on a sulfur group of donors
GO:0032542 sulfiredoxin activity

Parents of sulfiredoxin activity (GO:0032542)

subject	relation	object
sulfiredoxin activity	RO:0000057	ADP(3-) (CHEBI:456216)
sulfiredoxin activity	RO:0000057	3-sulfino-L-alanine(1-) residue (CHEBI:61974)
sulfiredoxin activity	RO:0000057	L-cystine residue (CHEBI:50058)
sulfiredoxin activity	RO:0000057	S-hydroxy-L-cysteine residue (CHEBI:61973)
sulfiredoxin activity	is_a	antioxidant activity (GO:0016209)
sulfiredoxin activity	RO:0000057	ATP(4-) (CHEBI:30616)
sulfiredoxin activity	is_a	oxidoreductase activity, acting on a sulfur group of donors (GO:0016667)
sulfiredoxin activity	RO:0000057	hydrogenphosphate (CHEBI:43474)
sulfiredoxin activity	RO:0000057	L-cysteine residue (CHEBI:29950)

This term has no children.

EC: 1.8.98.2
MetaCyc: 1.8.98.2-RXN
Reactome: R-HSA-9760094
RHEA: 17545