AmiGO 2: Term Details for "DNA recombinase mediator complex" (GO:0033061)

Accession: GO:0033061
Name: DNA recombinase mediator complex
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA through facilitating recombinase-RPA exchange. Source: PMID:12912992, GOC:vw, InterPro:IPR003488, GOC:elh, GOC:mah, PMID:32414915
Comment: Many paralogs of Rad51 act as recombinase mediators. These paralogs dimerize (or occasionally form tetramers) amongst themselves to form complexes with ssDNA-binding activity, and which act as mediators of Rad51 presynaptic filament assembly.
History: See term history for GO:0033061 at QuickGO
Chem. react.: None
Subset: goslim_pir
Related: Link to all genes and gene products annotated to DNA recombinase mediator complex (excluding "regulates").; Link to all direct and indirect annotations to DNA recombinase mediator complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for DNA recombinase mediator complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
DNA recombinase mediator complex	is_a	protein-containing complex (GO:0032991)

subject	relation	object
Rad51C-XRCC3 complex (GO:0033065)	is_a	DNA recombinase mediator complex
Swi5-Sfr1 complex (GO:0032798)	is_a	DNA recombinase mediator complex
Rad51B-Rad51C complex (GO:0033066)	is_a	DNA recombinase mediator complex
DNA recombinase mediator complex assembly (GO:1903871)	RO:0002588	DNA recombinase mediator complex
Rad51B-Rad51C-Rad51D-XRCC2 complex (GO:0033063)	is_a	DNA recombinase mediator complex
XRCC2-RAD51D complex (GO:0033064)	is_a	DNA recombinase mediator complex

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