Term Information

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Accession
GO:0033188
Name
sphingomyelin synthase activity
Ontology
molecular_function
Synonyms
SM synthase activity, SMS1, SMS2, ceramide:phosphatidylcholine cholinephosphotransferase activity, phosphatidylcholine:ceramide cholinephosphotransferase activity
Alternate IDs
None
Definition
Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin. Source: EC:2.7.8.27, RHEA:18765
Comment
None
History
See term history for GO:0033188 at QuickGO
Chem. react.
has participant N-acylsphingosine
has participant 1,2-diacyl-sn-glycero-3-phosphocholine
has participant sphingomyelin d18:1
has participant 1,2-diacyl-sn-glycerol
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of sphingomyelin synthase activity (GO:0033188)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
sphingomyelin synthase activity [RO:0000057 relation] RO:0000057  N-acylsphingosine (CHEBI:52639)
sphingomyelin synthase activity [RO:0000057 relation] RO:0000057  1,2-diacyl-sn-glycero-3-phosphocholine (CHEBI:57643)
sphingomyelin synthase activity [RO:0000057 relation] RO:0000057  sphingomyelin d18:1 (CHEBI:17636)
sphingomyelin synthase activity [RO:0000057 relation] RO:0000057  1,2-diacyl-sn-glycerol (CHEBI:17815)
sphingomyelin synthase activity [is_a relation] is_a  phosphotransferase activity, for other substituted phosphate groups (GO:0016780)

This term has no children.

EC
2.7.8.27
KEGG_REACTION
R08969
MetaCyc
2.7.8.27-RXN
Reactome
R-HSA-429798
R-HSA-429786
RHEA
18765