Term Information

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Accession
GO:0033209
Name
tumor necrosis factor-mediated signaling pathway
Ontology
biological_process
Synonyms
tumor necrosis factor-mediated signalling pathway, adipocytokine signaling pathway, TNF-alpha-mediated signaling pathway, tumor necrosis factor alpha-mediated signaling pathway
Alternate IDs
None
Definition
The series of molecular signals initiated by tumor necrosis factor binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Source: GOC:signaling, GOC:mah
Comment
None
History
See term history for GO:0033209 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of tumor necrosis factor-mediated signaling pathway (GO:0033209)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tumor necrosis factor-mediated signaling pathway [is_a relation] is_a  cytokine-mediated signaling pathway (GO:0019221)
tumor necrosis factor-mediated signaling pathway [BFO:0000050 relation] BFO:0000050  cellular response to tumor necrosis factor (GO:0071356)
Children of tumor necrosis factor-mediated signaling pathway (GO:0033209)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of tumor necrosis factor-mediated signaling pathway (GO:0010803) [RO:0002211 relation] RO:0002211  tumor necrosis factor-mediated signaling pathway
negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) [RO:0002212 relation] RO:0002212  tumor necrosis factor-mediated signaling pathway
tumor necrosis factor receptor activity (GO:0005031) [BFO:0000050 relation] BFO:0000050  tumor necrosis factor-mediated signaling pathway
positive regulation of tumor necrosis factor-mediated signaling pathway (GO:1903265) [RO:0002213 relation] RO:0002213  tumor necrosis factor-mediated signaling pathway
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