Term Information

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Accession
GO:0033210
Name
leptin-mediated signaling pathway
Ontology
biological_process
Synonyms
leptin-mediated signalling pathway, adipocytokine signaling pathway
Alternate IDs
None
Definition
The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. Source: GOC:signaling, GOC:yaf, GOC:mah
Comment
None
History
See term history for GO:0033210 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0033210 from QuickGO

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Parents of leptin-mediated signaling pathway (GO:0033210)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
leptin-mediated signaling pathway [BFO:0000050 relation] BFO:0000050  cellular response to leptin stimulus (GO:0044320)
leptin-mediated signaling pathway [is_a relation] is_a  cytokine-mediated signaling pathway (GO:0019221)
Children of leptin-mediated signaling pathway (GO:0033210)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
leptin receptor activity (GO:0038021) [BFO:0000050 relation] BFO:0000050  leptin-mediated signaling pathway
negative regulation of appetite by leptin-mediated signaling pathway (GO:0038108) [is_a relation] is_a  leptin-mediated signaling pathway
None.