Term Information

Feedback 
Accession
GO:0033290
Name
eukaryotic 48S preinitiation complex
Ontology
cellular_component
Synonyms
eukaryotic 48S pre-initiation complex, eukaryotic 48S initiation complex
Alternate IDs
GO:0016283
Definition
The protein-ribosome-tRNA complex that has just recognized the start codon of a capped mRNA. It is composed of the small ribosomal subunit, eukaryote initiation factors (eIF) eIF3 complex, eIF1, eIF1A, eIF2-GDP, eIF4 complex and initiatior-methionine-tRNA. Recognition of the start codon triggers downstream steps in the pathway, including eIF1 dissociation; Pi release from eIF2; and conversion to the closed, scanning-arrested conformation of the PIC. Source: PMID:16510876, PMID:24499181, PMID:24319994, PMID:29735639, GOC:hjd
Comment
None
History
See term history for GO:0033290 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

Loading...
pending...
View this term in QuickGO.

Graph of GO:0033290 from QuickGO

Additional external viewing options
Additional internal viewing options
Parents of eukaryotic 48S preinitiation complex (GO:0033290)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
eukaryotic 48S preinitiation complex [RO:0002160 relation] RO:0002160  Eukaryota (NCBITaxon:2759)
eukaryotic 48S preinitiation complex [is_a relation] is_a  translation preinitiation complex (GO:0070993)
eukaryotic 48S preinitiation complex [BFO:0000051 relation] BFO:0000051  cytosolic small ribosomal subunit (GO:0022627)

This term has no children.

GONUTS Add usage comments for this term on the GONUTS wiki.