Term Information

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Accession
GO:0033503
Name
HULC complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A ubiquitin ligase complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp6, Shf1, Brl2/Rfp1 and Brl1/Rfp2. Source: PMID:17374714, GOC:mah, PMID:17363370
Comment
None
History
See term history for GO:0033503 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of HULC complex (GO:0033503)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
HULC complex [is_a relation] is_a  ubiquitin ligase complex (GO:0000151)
HULC complex [is_a relation] is_a  ubiquitin conjugating enzyme complex (GO:0031371)
HULC complex [BFO:0000050 relation] BFO:0000050  chromatin (GO:0000785)
HULC complex [RO:0002162 relation] RO:0002162  cellular organisms (NCBITaxon:131567)

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