AmiGO 2: Term Details for "integrin activation" (GO:0033622)

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Term Information

Accession: GO:0033622
Name: integrin activation
Ontology: biological_process
Synonyms: integrin complex activation, integrin complex assembly
Alternate IDs: None
Definition: The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands. Source: PMID:14754902, GOC:add, PMID:12213832
Comment: None
History: See term history for GO:0033622 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to integrin activation (excluding "regulates").; Link to all direct and indirect annotations to integrin activation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for integrin activation (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0071840 cellular component organization or biogenesis
GO:0044085 cellular component biogenesis
GO:0016043 cellular component organization
GO:0022607 cellular component assembly
GO:0043933 protein-containing complex organization
GO:0065003 protein-containing complex assembly
GO:0033622 integrin activation
GO:0033624 negative regulation of integrin activation
GO:0033625 positive regulation of integrin activation
GO:0033623 regulation of integrin activation

Parents of integrin activation (GO:0033622)

subject	relation	object
integrin activation	RO:0002588	integrin complex (GO:0008305)
integrin activation	is_a	protein-containing complex assembly (GO:0065003)

Children of integrin activation (GO:0033622)

subject	relation	object
positive regulation of integrin activation (GO:0033625)	RO:0002213	integrin activation
regulation of integrin activation (GO:0033623)	RO:0002211	integrin activation
negative regulation of integrin activation (GO:0033624)	RO:0002212	integrin activation

integrin activation