Term Information

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Accession
GO:0033703
Name
3beta-hydroxy-5beta-steroid dehydrogenase activity
Ontology
molecular_function
Synonyms
3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase activity, 3beta-hydroxysteroid 5beta-oxidoreductase activity, 3beta-hydroxysteroid 5beta-progesterone oxidoreductase activity
Alternate IDs
None
Definition
Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP+ = 5beta-pregnan-3,20-dione + H+ + NADPH. Source: EC:1.1.1.277, RHEA:22944
Comment
None
History
See term history for GO:0033703 at QuickGO
Chem. react.
has participant 5beta-pregnane-3,20-dione
has participant NADP(3-)
has participant NADPH(4-)
has participant 3beta-hydroxy-5beta-pregnan-20-one
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of 3beta-hydroxy-5beta-steroid dehydrogenase activity (GO:0033703)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
3beta-hydroxy-5beta-steroid dehydrogenase activity [RO:0000057 relation] RO:0000057  5beta-pregnane-3,20-dione (CHEBI:30154)
3beta-hydroxy-5beta-steroid dehydrogenase activity [RO:0000057 relation] RO:0000057  NADP(3-) (CHEBI:58349)
3beta-hydroxy-5beta-steroid dehydrogenase activity [RO:0000057 relation] RO:0000057  NADPH(4-) (CHEBI:57783)
3beta-hydroxy-5beta-steroid dehydrogenase activity [RO:0000057 relation] RO:0000057  3beta-hydroxy-5beta-pregnan-20-one (CHEBI:16229)
3beta-hydroxy-5beta-steroid dehydrogenase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
3beta-hydroxy-5beta-steroid dehydrogenase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)

This term has no children.

EC
1.1.1.277
KEGG_REACTION
R06166
MetaCyc
1.1.1.277-RXN
RHEA
22944