AmiGO 2: Term Details for "peptide-methionine (R)-S-oxide reductase activity" (GO:0033743)

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Term Information

Accession: GO:0033743
Name: peptide-methionine (R)-S-oxide reductase activity
Ontology: molecular_function
Synonyms: protein-methionine-R-oxide reductase activity, MsrB, PilB, SelR, SelX, methionine S-oxide reductase (R-form oxidizing) activity, pMRsr, pMSR, peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity, selenoprotein R, methionine sulfoxide reductase B activity, methionine S-oxide reductase activity, methionine sulfoxide reductase activity
Alternate IDs: GO:0000318
Definition: Catalysis of the reaction: peptide-L-methionine + H2O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin. Source: EC:1.8.4.12, GOC:vw, GOC:mah, RHEA:24164
Comment: None
History: See term history for GO:0033743 at QuickGO
Chem. react.: has participant L-cystine residue; has participant water; has participant L-methionine (R)-S-oxide residue; has participant L-methionine residue; has participant L-cysteine residue
Subset: None
Related: Link to all genes and gene products annotated to peptide-methionine (R)-S-oxide reductase activity (excluding "regulates").; Link to all direct and indirect annotations to peptide-methionine (R)-S-oxide reductase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for peptide-methionine (R)-S-oxide reductase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016667 oxidoreductase activity, acting on a sulfur group of donors
GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
GO:0033743 peptide-methionine (R)-S-oxide reductase activity

Parents of peptide-methionine (R)-S-oxide reductase activity (GO:0033743)

subject	relation	object
peptide-methionine (R)-S-oxide reductase activity	is_a	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor (GO:0016671)
peptide-methionine (R)-S-oxide reductase activity	RO:0000057	L-cystine residue (CHEBI:50058)
peptide-methionine (R)-S-oxide reductase activity	RO:0000057	water (CHEBI:15377)
peptide-methionine (R)-S-oxide reductase activity	RO:0000057	L-methionine (R)-S-oxide residue (CHEBI:45764)
peptide-methionine (R)-S-oxide reductase activity	RO:0000057	L-methionine residue (CHEBI:16044)
peptide-methionine (R)-S-oxide reductase activity	RO:0000057	L-cysteine residue (CHEBI:29950)

This term has no children.

EC: 1.8.4.12
KEGG_REACTION: R07607
MetaCyc: 1.8.4.12-RXN
Reactome: R-HSA-5676917
RHEA: 24164