AmiGO 2: Term Details for "7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity" (GO:0033778)

Accession: GO:0033778
Name: 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity
Ontology: molecular_function
Synonyms: 7alpha-hydroxy-4-cholesten-3-one 12alpha-monooxygenase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H+ + NADPH + O2 = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H2O + NADP+. Source: RHEA:46752, PMID:10051404, PMID:1400444
Comment: None
History: See term history for GO:0033778 at QuickGO
Chem. react.: has participant water; has participant FMN(3-); has participant dioxygen; has participant 7alpha,12alpha-dihydroxycholest-4-en-3-one; has participant FMNH2(2-); has participant 7alpha-hydroxycholest-4-en-3-one; has participant hydron
Subset: None
Related: Link to all genes and gene products annotated to 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity (excluding "regulates").; Link to all direct and indirect annotations to 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	RO:0000057	water (CHEBI:15377)
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	RO:0000057	FMN(3-) (CHEBI:58210)
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	is_a	sterol 12-alpha-hydroxylase activity (GO:0008397)
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	RO:0000057	dioxygen (CHEBI:15379)
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	RO:0000057	7alpha,12alpha-dihydroxycholest-4-en-3-one (CHEBI:28477)
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	RO:0000057	FMNH2(2-) (CHEBI:57618)
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	RO:0000057	7alpha-hydroxycholest-4-en-3-one (CHEBI:17899)
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	RO:0000057	hydron (CHEBI:15378)

This term has no children.