Term Information

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Accession
GO:0033780
Name
taurochenodeoxycholate 6alpha-hydroxylase activity
Ontology
molecular_function
Synonyms
CYP3A4, CYP4A21, taurochenodeoxycholate 6alpha-monooxygenase activity, taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity
Alternate IDs
None
Definition
Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O. Source: RHEA:23644
Comment
None
History
See term history for GO:0033780 at QuickGO
Chem. react.
has participant lithocholate
has participant hyodeoxycholate
has participant FMN(3-)
has participant FMNH2(2-)
has participant dioxygen
has participant hydron
has participant water
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of taurochenodeoxycholate 6alpha-hydroxylase activity (GO:0033780)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
taurochenodeoxycholate 6alpha-hydroxylase activity [RO:0000057 relation] RO:0000057  lithocholate (CHEBI:29744)
taurochenodeoxycholate 6alpha-hydroxylase activity [RO:0000057 relation] RO:0000057  hyodeoxycholate (CHEBI:58875)
taurochenodeoxycholate 6alpha-hydroxylase activity [RO:0000057 relation] RO:0000057  FMN(3-) (CHEBI:58210)
taurochenodeoxycholate 6alpha-hydroxylase activity [RO:0000057 relation] RO:0000057  FMNH2(2-) (CHEBI:57618)
taurochenodeoxycholate 6alpha-hydroxylase activity [RO:0000057 relation] RO:0000057  dioxygen (CHEBI:15379)
taurochenodeoxycholate 6alpha-hydroxylase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
taurochenodeoxycholate 6alpha-hydroxylase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)
taurochenodeoxycholate 6alpha-hydroxylase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)

This term has no children.

EC
1.14.14.57
MetaCyc
RXN-7977
RHEA
23644