AmiGO 2: Term Details for "24-hydroxycholesterol 7alpha-hydroxylase activity" (GO:0033782)

Accession: GO:0033782
Name: 24-hydroxycholesterol 7alpha-hydroxylase activity
Ontology: molecular_function
Synonyms: 24-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity, 24-hydroxycholesterol 7alpha-monooxygenase activity
Alternate IDs: None
Definition: Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase]. Source: PMID:10748047, RHEA:46124, PMID:11013305
Comment: Formerly EC:1.14.13.99.
History: See term history for GO:0033782 at QuickGO
Chem. react.: has participant FMNH2(2-); has participant hydron; has participant FMN(3-); has participant dioxygen; has participant water; has participant (24S)-7alpha,24-dihydroxycholesterol; has participant (24S)-24-hydroxycholesterol
Subset: None
Related: Link to all genes and gene products annotated to 24-hydroxycholesterol 7alpha-hydroxylase activity (excluding "regulates").; Link to all direct and indirect annotations to 24-hydroxycholesterol 7alpha-hydroxylase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 24-hydroxycholesterol 7alpha-hydroxylase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
24-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	FMNH2(2-) (CHEBI:57618)
24-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	hydron (CHEBI:15378)
24-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	FMN(3-) (CHEBI:58210)
24-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	dioxygen (CHEBI:15379)
24-hydroxycholesterol 7alpha-hydroxylase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (GO:0016712)
24-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	water (CHEBI:15377)
24-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	(24S)-7alpha,24-dihydroxycholesterol (CHEBI:37640)
24-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	(24S)-24-hydroxycholesterol (CHEBI:34310)

This term has no children.