AmiGO 2: Term Details for "25-hydroxycholesterol 7alpha-hydroxylase activity" (GO:0033783)

Accession: GO:0033783
Name: 25-hydroxycholesterol 7alpha-hydroxylase activity
Ontology: molecular_function
Synonyms: 25-hydroxycholesterol 7alpha-monooxygenase activity, CYP7B1, CYP7B1 oxysterol 7alpha-hydroxylase activity, cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity
Alternate IDs: None
Definition: Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O. Source: EC:1.14.14.29
Comment: None
History: See term history for GO:0033783 at QuickGO
Chem. react.: has participant FMN(3-); has participant hydron; has participant (25R)-7alpha,26-dihydroxycholesterol; has participant water; has participant (25R)-cholest-5-ene-3beta,26-diol; has participant FMNH2(2-); has participant dioxygen
Subset: None
Related: Link to all genes and gene products annotated to 25-hydroxycholesterol 7alpha-hydroxylase activity (excluding "regulates").; Link to all direct and indirect annotations to 25-hydroxycholesterol 7alpha-hydroxylase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 25-hydroxycholesterol 7alpha-hydroxylase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
25-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	FMN(3-) (CHEBI:58210)
25-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	hydron (CHEBI:15378)
25-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	(25R)-7alpha,26-dihydroxycholesterol (CHEBI:76592)
25-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	water (CHEBI:15377)
25-hydroxycholesterol 7alpha-hydroxylase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)
25-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	(25R)-cholest-5-ene-3beta,26-diol (CHEBI:76591)
25-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	FMNH2(2-) (CHEBI:57618)
25-hydroxycholesterol 7alpha-hydroxylase activity	RO:0000057	dioxygen (CHEBI:15379)

This term has no children.