AmiGO 2: Term Details for "VCP-NPL4-UFD1 AAA ATPase complex" (GO:0034098)

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Term Information

Accession: GO:0034098
Name: VCP-NPL4-UFD1 AAA ATPase complex
Ontology: cellular_component
Synonyms: p97-Ufd1-Npl4 complex, Cdc48p-Npl4p-Ufd1p AAA ATPase complex
Alternate IDs: None
Definition: A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry). Source: PMID:16179952, PMID:11813000
Comment: None
History: See term history for GO:0034098 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to VCP-NPL4-UFD1 AAA ATPase complex (excluding "regulates").; Link to all direct and indirect annotations to VCP-NPL4-UFD1 AAA ATPase complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for VCP-NPL4-UFD1 AAA ATPase complex (excluding "regulates").

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CARO:0030000 biological entity
GO:0009987 cellular process
CARO:0000000 anatomical entity
GO:0051179 localization
GO:0008152 metabolic process
UBERON:0001062 anatomical entity
GO:0008150 biological_process
GO:0009056 catabolic process
GO:0051641 cellular localization
GO:0051234 establishment of localization
GO:0033036 macromolecule localization
GO:0043170 macromolecule metabolic process
CARO:0000006 material anatomical entity
GO:0044238 primary metabolic process
GO:0008104 protein localization
GO:0019538 protein metabolic process
GO:0050896 response to stimulus
GO:0006810 transport
UBERON:0000061 anatomical structure
CL:0000000 cell
GO:0110165 cellular anatomical structure
GO:0070727 cellular macromolecule localization
GO:0051716 cellular response to stimulus
CARO:0000003 connected anatomical structure
GO:0045184 establishment of protein localization
GO:0005622 intracellular anatomical structure
GO:0009057 macromolecule catabolic process
UBERON:0000465 material anatomical entity
GO:0071705 nitrogen compound transport
GO:0043226 organelle
GO:0030163 protein catabolic process
GO:0006508 proteolysis
GO:0006950 response to stress
GO:0033554 cellular response to stress
GO:0005575 cellular_component
GO:0051649 establishment of localization in cell
GO:0043229 intracellular organelle
GO:0046907 intracellular transport
GO:0043227 membrane-bounded organelle
GO:0015031 protein transport
GO:0051603 proteolysis involved in protein catabolic process
GO:0042221 response to chemical
GO:0005737 cytoplasm
GO:0012505 endomembrane system
GO:0005783 endoplasmic reticulum
GO:0043231 intracellular membrane-bounded organelle
GO:0006886 intracellular protein transport
GO:0016020 membrane
GO:0031984 organelle subcompartment
GO:0010498 proteasomal protein catabolic process
GO:0034976 response to endoplasmic reticulum stress
GO:1901698 response to nitrogen compound
GO:0098827 endoplasmic reticulum subcompartment
GO:1903513 endoplasmic reticulum to cytosol transport
GO:0036503 ERAD pathway
GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network
GO:0031090 organelle membrane
GO:0032527 protein exit from endoplasmic reticulum
GO:0032991 protein-containing complex
GO:0005789 endoplasmic reticulum membrane
GO:0140534 endoplasmic reticulum protein-containing complex
GO:0098796 membrane protein complex
GO:0030970 retrograde protein transport, ER to cytosol
GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex

Parents of VCP-NPL4-UFD1 AAA ATPase complex (GO:0034098)

subject	relation	object
VCP-NPL4-UFD1 AAA ATPase complex	is_a	endoplasmic reticulum protein-containing complex (GO:0140534)
VCP-NPL4-UFD1 AAA ATPase complex	RO:0002216	retrograde protein transport, ER to cytosol (GO:0030970)
VCP-NPL4-UFD1 AAA ATPase complex	RO:0002162	Eukaryota (NCBITaxon:2759)
VCP-NPL4-UFD1 AAA ATPase complex	BFO:0000051	UFD1-NPL4 complex (GO:0036501)
VCP-NPL4-UFD1 AAA ATPase complex	BFO:0000050	endoplasmic reticulum membrane (GO:0005789)
VCP-NPL4-UFD1 AAA ATPase complex	is_a	membrane protein complex (GO:0098796)

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