Term Information

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Accession
GO:0034647
Name
histone H3K4me/H3K4me2/H3K4me3 demethylase activity
Ontology
molecular_function
Synonyms
histone H3-tri/di/monomethyl-lysine-4 demethylase activity, histone demethylase activity (H3-K4-me3 specific), histone demethylase activity (H3-trimethyl-K4 specific), H3K4me3 demethylase activity, histone H3-K4me3 demethylase activity, histone H3-K4me2 demethylase activity, histone H3K4me2 demethylase activity
Alternate IDs
None
Definition
Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. Source: PMID:17550896, PMID:22473470
Comment
None
History
See term history for GO:0034647 at QuickGO
Chem. react.
has participant formaldehyde
has participant L-lysinium residue
has participant dioxygen
has participant carbon dioxide
has participant 2-oxoglutarate(2-)
has participant N(6),N(6),N(6)-trimethyl-L-lysine residue
has participant succinate(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0034647 from QuickGO

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Parents of histone H3K4me/H3K4me2/H3K4me3 demethylase activity (GO:0034647)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
histone H3K4me/H3K4me2/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  formaldehyde (CHEBI:16842)
histone H3K4me/H3K4me2/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  L-lysinium residue (CHEBI:29969)
histone H3K4me/H3K4me2/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  dioxygen (CHEBI:15379)
histone H3K4me/H3K4me2/H3K4me3 demethylase activity [is_a relation] is_a  2-oxoglutarate-dependent dioxygenase activity (GO:0016706)
histone H3K4me/H3K4me2/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  carbon dioxide (CHEBI:16526)
histone H3K4me/H3K4me2/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  2-oxoglutarate(2-) (CHEBI:16810)
histone H3K4me/H3K4me2/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  N(6),N(6),N(6)-trimethyl-L-lysine residue (CHEBI:61961)
histone H3K4me/H3K4me2/H3K4me3 demethylase activity [RO:0000057 relation] RO:0000057  succinate(2-) (CHEBI:30031)
histone H3K4me/H3K4me2/H3K4me3 demethylase activity [is_a relation] is_a  histone H3K4 demethylase activity (GO:0032453)

This term has no children.

EC
1.14.11.67
RHEA
60208