AmiGO 2: Term Details for "ESC/E(Z) complex" (GO:0035098)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0035098
Name: ESC/E(Z) complex
Ontology: cellular_component
Synonyms: Extra Sex Combs/Enhancer of Zeste complex, PRC2 complex
Alternate IDs: None
Definition: A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4. Source: PMID:12408864, GOC:sp, PMID:12408863, GOC:bf, PMID:20064375
Comment: None
History: See term history for GO:0035098 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to ESC/E(Z) complex (excluding "regulates").; Link to all direct and indirect annotations to ESC/E(Z) complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for ESC/E(Z) complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0008150 biological_process
GO:0009987 cellular process
GO:0071840 cellular component organization or biogenesis
CARO:0030000 biological entity
GO:0016043 cellular component organization
CARO:0000000 anatomical entity
GO:0110165 cellular anatomical entity
GO:0043933 protein-containing complex organization
UBERON:0001062 anatomical entity
GO:0005622 intracellular anatomical structure
CARO:0000006 material anatomical entity
GO:0031974 membrane-enclosed lumen
GO:0003674 molecular_function
GO:0043226 organelle
GO:0071824 protein-DNA complex organization
UBERON:0000061 anatomical structure
GO:0003824 catalytic activity
GO:0006325 chromatin organization
CARO:0000003 connected anatomical structure
GO:0043229 intracellular organelle
UBERON:0000465 material anatomical entity
GO:0043227 membrane-bounded organelle
GO:0043233 organelle lumen
GO:0032991 protein-containing complex
GO:0016740 transferase activity
GO:0140096 catalytic activity, acting on a protein
GO:1902494 catalytic complex
CL:0000000 cell
GO:0005575 cellular_component
GO:0006338 chromatin remodeling
GO:0043231 intracellular membrane-bounded organelle
GO:0070013 intracellular organelle lumen
GO:0008168 methyltransferase activity
GO:0005634 nucleus
PR:000050567 protein-containing material entity
GO:0016741 transferase activity, transferring one-carbon groups
GO:0140993 histone modifying activity
GO:0031981 nuclear lumen
GO:0008276 protein methyltransferase activity
GO:1990234 transferase complex
GO:0042054 histone methyltransferase activity
GO:0034708 methyltransferase complex
GO:0140513 nuclear protein-containing complex
GO:0005654 nucleoplasm
GO:0035097 histone methyltransferase complex
GO:0031519 PcG protein complex
GO:0035098 ESC/E(Z) complex

Parents of ESC/E(Z) complex (GO:0035098)

subject	relation	object
ESC/E(Z) complex	is_a	PcG protein complex (GO:0031519)
ESC/E(Z) complex	is_a	histone methyltransferase complex (GO:0035097)

This term has no children.

GONUTS Add usage comments for this term on the GONUTS wiki.