AmiGO 2: Term Details for "protein-arginine omega-N monomethyltransferase activity" (GO:0035241)

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Term Information

Accession: GO:0035241
Name: protein-arginine omega-N monomethyltransferase activity
Ontology: molecular_function
Synonyms: protein arginine omega-N monomethylase activity, S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega-methyl-L-arginine-forming), type III protein arginine methyltransferase activity
Alternate IDs: None
Definition: Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine. Source: PMID:14705965, EC:2.1.1.321, RESID:AA0069
Comment: Type III protein arginine methyltransferases catalyze the single methylation of one of the terminal nitrogen atoms of the guanidino group in an L-arginine residue within a protein. Unlike type I and type II protein arginine methyltransferases, which also catalyze this reaction, type III enzymes do not methylate the substrate any further.
History: See term history for GO:0035241 at QuickGO
Chem. react.: has participant N(omega)-methyl-argininium(1+) residue; has participant S-adenosyl-L-methionine zwitterion; has participant S-adenosyl-L-homocysteine zwitterion; has participant hydron; has participant L-argininium residue
Subset: None
Related: Link to all genes and gene products annotated to protein-arginine omega-N monomethyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations to protein-arginine omega-N monomethyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for protein-arginine omega-N monomethyltransferase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016740 transferase activity
GO:0008168 methyltransferase activity
GO:0016741 transferase activity, transferring one-carbon groups
GO:0140096 catalytic activity, acting on a protein
GO:0008170 N-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0016273 arginine N-methyltransferase activity
GO:0008276 protein methyltransferase activity
GO:0016274 protein-arginine N-methyltransferase activity
GO:0035241 protein-arginine omega-N monomethyltransferase activity

Parents of protein-arginine omega-N monomethyltransferase activity (GO:0035241)

subject	relation	object
protein-arginine omega-N monomethyltransferase activity	is_a	protein-arginine N-methyltransferase activity (GO:0016274)
protein-arginine omega-N monomethyltransferase activity	RO:0000057	N(omega)-methyl-argininium(1+) residue (CHEBI:65280)
protein-arginine omega-N monomethyltransferase activity	RO:0000057	S-adenosyl-L-methionine zwitterion (CHEBI:59789)
protein-arginine omega-N monomethyltransferase activity	RO:0000057	S-adenosyl-L-homocysteine zwitterion (CHEBI:57856)
protein-arginine omega-N monomethyltransferase activity	RO:0000057	hydron (CHEBI:15378)
protein-arginine omega-N monomethyltransferase activity	RO:0000057	L-argininium residue (CHEBI:29965)

This term has no children.

EC: 2.1.1.321
MetaCyc: 2.1.1.124-RXN
RHEA: 48100