Term Information

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Accession
GO:0035581
Name
sequestering of extracellular ligand from receptor
Ontology
biological_process
Synonyms
extracellular sequestering of receptor ligand, negative regulation of protein bioavailability
Alternate IDs
None
Definition
The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor. Source: GOC:signaling, GOC:BHF
Comment
Preventing a ligand from binding to its cell surface receptor be achieved by binding to the ligand directly, or by binding to members of a ligand-containing complex.
History
See term history for GO:0035581 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of sequestering of extracellular ligand from receptor (GO:0035581)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
sequestering of extracellular ligand from receptor [is_a relation] is_a  extracellular negative regulation of signal transduction (GO:1900116)
Children of sequestering of extracellular ligand from receptor (GO:0035581)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
sequestering of BMP from receptor via BMP binding (GO:0038098) [is_a relation] is_a  sequestering of extracellular ligand from receptor
sequestering of TGFbeta from receptor via TGFbeta binding (GO:0038105) [is_a relation] is_a  sequestering of extracellular ligand from receptor
sequestering of BMP in extracellular matrix (GO:0035582) [is_a relation] is_a  sequestering of extracellular ligand from receptor
sequestering of TGFbeta in extracellular matrix (GO:0035583) [is_a relation] is_a  sequestering of extracellular ligand from receptor
sequestering of nodal from receptor via nodal binding (GO:0038101) [is_a relation] is_a  sequestering of extracellular ligand from receptor
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