AmiGO 2: Term Details for "sequestering of BMP in extracellular matrix" (GO:0035582)

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Term Information

Accession: GO:0035582
Name: sequestering of BMP in extracellular matrix
Ontology: biological_process
Synonyms: BMP sequestration in the ECM, negative regulation of BMP signaling pathway by extracellular sequestering of BMP, negative regulation of BMP signalling pathway by extracellular matrix sequestering of BMP, negative regulation of bone morphogenetic protein signaling pathway by extracellular matrix sequestering of bone morphogenetic protein
Alternate IDs: None
Definition: Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins. Source: GOC:BHF, PMID:20855508
Comment: Confining BMP in the extracellular matrix may be achieved by binding BMP directly, or by binding to members of a BMP-containing complex.
History: See term history for GO:0035582 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to sequestering of BMP in extracellular matrix (excluding "regulates").; Link to all direct and indirect annotations to sequestering of BMP in extracellular matrix (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for sequestering of BMP in extracellular matrix (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
CARO:0000006 material anatomical entity
GO:0008150 biological_process
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0065007 biological regulation
GO:0007154 cell communication
GO:0009987 cellular process
GO:0005575 cellular_component
GO:0051179 localization
GO:0048519 negative regulation of biological process
GO:0050789 regulation of biological process
GO:0050794 regulation of cellular process
GO:0050896 response to stimulus
GO:0007165 signal transduction
GO:0023052 signaling
GO:0007166 cell surface receptor signaling pathway
GO:0110165 cellular anatomical entity
GO:0051641 cellular localization
GO:0051716 cellular response to stimulus
GO:0033036 macromolecule localization
GO:0048523 negative regulation of cellular process
GO:0010646 regulation of cell communication
GO:0048583 regulation of response to stimulus
GO:0023051 regulation of signaling
GO:0009719 response to endogenous stimulus
GO:0070848 response to growth factor
GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway
GO:0070727 cellular macromolecule localization
GO:0071495 cellular response to endogenous stimulus
GO:0071363 cellular response to growth factor stimulus
GO:0007167 enzyme-linked receptor protein signaling pathway
GO:0005576 extracellular region
GO:0010648 negative regulation of cell communication
GO:0048585 negative regulation of response to stimulus
GO:0023057 negative regulation of signaling
GO:0009966 regulation of signal transduction
GO:0071772 response to BMP
GO:0030509 BMP signaling pathway
GO:0071773 cellular response to BMP stimulus
GO:1900115 extracellular regulation of signal transduction
GO:0051235 maintenance of location
GO:0009968 negative regulation of signal transduction
GO:0008104 protein localization
GO:0090287 regulation of cellular response to growth factor stimulus
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0141091 transforming growth factor beta receptor superfamily signaling pathway
GO:1900116 extracellular negative regulation of signal transduction
GO:0045185 maintenance of protein location
GO:0090288 negative regulation of cellular response to growth factor stimulus
GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0071692 protein localization to extracellular region
GO:0030510 regulation of BMP signaling pathway
GO:0071694 maintenance of protein location in extracellular region
GO:0030514 negative regulation of BMP signaling pathway
GO:0035581 sequestering of extracellular ligand from receptor
GO:0035582 sequestering of BMP in extracellular matrix

Parents of sequestering of BMP in extracellular matrix (GO:0035582)

subject	relation	object
sequestering of BMP in extracellular matrix	is_a	sequestering of extracellular ligand from receptor (GO:0035581)
sequestering of BMP in extracellular matrix	is_a	negative regulation of BMP signaling pathway (GO:0030514)
sequestering of BMP in extracellular matrix	is_a	maintenance of protein location in extracellular region (GO:0071694)

This term has no children.