Term Information

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Accession
GO:0035633
Name
maintenance of blood-brain barrier
Ontology
biological_process
Synonyms
maintenance of BBB, maintenance of blood/brain barrier
Alternate IDs
None
Definition
Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation. Source: PMID:20080302, GOC:bc, GOC:bf, GOC:aruk, PMID:30280653, GOC:sl
Comment
Homeostasis and maintenance processes are regulatory processes, therefore, regulation child terms, such as: regulation of maintenance of blood-brain barrier, should not exist for these terms. Instead, for capturing regulation at the blood-brain barrier, consider using the part_of child term: regulation of blood-brain barrier permeability.
History
See term history for GO:0035633 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of maintenance of blood-brain barrier (GO:0035633)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
maintenance of blood-brain barrier [is_a relation] is_a  tissue homeostasis (GO:0001894)
maintenance of blood-brain barrier [RO:0002162 relation] RO:0002162  Eumetazoa (NCBITaxon:6072)
Children of maintenance of blood-brain barrier (GO:0035633)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of blood-brain barrier permeability (GO:1905603) [BFO:0000050 relation] BFO:0000050  maintenance of blood-brain barrier
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