AmiGO 2: Term Details for "ciliary transition zone" (GO:0035869)

Term Information

Accession: GO:0035869
Name: ciliary transition zone
Ontology: cellular_component
Synonyms: cilial transition zone, cilium transition zone, connecting cilium
Alternate IDs: None
Definition: A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm. Source: PMID:21422230, GOC:cilia, GOC:kmv
Comment: Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone.
History: See term history for GO:0035869 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to ciliary transition zone (excluding "regulates").; Link to all direct and indirect annotations to ciliary transition zone (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for ciliary transition zone (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0000061 anatomical structure
UBERON:0001062 anatomical entity
CL:0000000 cell
GO:0110165 cellular anatomical entity
CARO:0000006 material anatomical entity
GO:0042995 cell projection
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0043226 organelle
GO:0005575 cellular_component
GO:0043227 membrane-bounded organelle
GO:0120025 plasma membrane bounded cell projection
PR:000050567 protein-containing material entity
GO:0005929 cilium
GO:0035869 ciliary transition zone
GO:1990805 central cylinder
GO:0097538 ciliary necklace
GO:0036038 MKS complex
GO:1990957 NPHP complex
GO:0032391 photoreceptor connecting cilium
GO:0097537 Y-shaped link

Parents of ciliary transition zone (GO:0035869)

subject	relation	object
ciliary transition zone	BFO:0000050	cilium (GO:0005929)
ciliary transition zone	RO:0002162	Eukaryota (NCBITaxon:2759)
ciliary transition zone	is_a	cellular anatomical entity (GO:0110165)

Children of ciliary transition zone (GO:0035869)

subject	relation	object
MKS complex (GO:0036038)	BFO:0000050	ciliary transition zone
ciliary base (GO:0097546)	BFO:0000051	ciliary transition zone
ciliary transition zone assembly (GO:1905349)	RO:0002588	ciliary transition zone
central cylinder (GO:1990805)	BFO:0000050	ciliary transition zone
ciliary necklace (GO:0097538)	BFO:0000050	ciliary transition zone
NPHP complex (GO:1990957)	BFO:0000050	ciliary transition zone
photoreceptor connecting cilium (GO:0032391)	is_a	ciliary transition zone
protein localization to ciliary transition zone (GO:1904491)	RO:0002339	ciliary transition zone
Y-shaped link (GO:0097537)	BFO:0000050	ciliary transition zone

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