Term Information

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Accession
GO:0035979
Name
histone H2AXS139 kinase activity
Ontology
molecular_function
Synonyms
histone H2AS139 kinase activity, histone kinase activity (H2A-S139 specific), histone kinase activity (H2A.x-S139 specific)
Alternate IDs
None
Definition
Catalysis of the reaction: histone H2AX-serine (position 139) + ATP = histone H2AX-phosphoserine (position 139) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 139 of histone variant H2AX. Source: GOC:yaf, PMID:16061642, PMID:11893489
Comment
Residue 1 of histone H2A is taken as the first residue following removal of the initiating Methionine (Met).
History
See term history for GO:0035979 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of histone H2AXS139 kinase activity (GO:0035979)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
histone H2AXS139 kinase activity [is_a relation] is_a  protein serine/threonine kinase activity (GO:0004674)
histone H2AXS139 kinase activity [is_a relation] is_a  histone H2AX kinase activity (GO:0141003)

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