OBSOLETE. The assembly of chromatin into senescence-associated heterochromatin foci (SAHF), transcriptionally-silent heterochromatin structures present in senescent cells, containing the condensed chromatin of one chromosome, and enriched for histone modifications. Formation of these chromatin structures is thought to repress expression of proliferation-promoting genes.
Source:PMID:15621527,
GOC:yaf,
PMID:21248468
Comment
This term was obsoleted because there is no evidence that this is a distinct process; this should be captured as an extension.
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to all genes and gene products annotated to obsolete senescence-associated heterochromatin focus assembly (excluding "regulates").
Link
to all direct and indirect annotations
to obsolete senescence-associated heterochromatin focus assembly (excluding "regulates").
Link
to all direct and indirect annotations download (limited to first 10,000)
for obsolete senescence-associated heterochromatin focus assembly (excluding "regulates").
