AmiGO 2: Term Details for "protein-succinyllysine desuccinylase activity" (GO:0036055)

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Term Information

Accession: GO:0036055
Name: protein-succinyllysine desuccinylase activity
Ontology: molecular_function
Synonyms: peptidyl-succinyllysine desuccinylase activity, succinyl lysine desuccinylase activity, succinyllysine desuccinylase activity
Alternate IDs: None
Definition: Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD+ = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide. Source: GOC:sp, PMID:22076378
Comment: This reaction is the removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue of a protein or peptide.
History: See term history for GO:0036055 at QuickGO
Chem. react.: has participant L-lysinium residue; has participant NAD(1-); has participant nicotinamide; has participant water; has participant 2''-O-succinyl-ADP-D-ribose(3-); has participant N(6)-succinyl-L-lysine(1-) residue
Subset: None
Related: Link to all genes and gene products annotated to protein-succinyllysine desuccinylase activity (excluding "regulates").; Link to all direct and indirect annotations to protein-succinyllysine desuccinylase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for protein-succinyllysine desuccinylase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0043170 macromolecule metabolic process
GO:1901564 organonitrogen compound metabolic process
GO:0044238 primary metabolic process
GO:0043412 macromolecule modification
GO:0003674 molecular_function
GO:0019538 protein metabolic process
GO:0003824 catalytic activity
GO:0098732 macromolecule deacylation
GO:0036211 protein modification process
GO:0016787 hydrolase activity
GO:0018193 peptidyl-amino acid modification
GO:0035601 protein deacylation
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0018205 peptidyl-lysine modification
GO:0036048 protein desuccinylation
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0036049 peptidyl-lysine desuccinylation
GO:0036055 protein-succinyllysine desuccinylase activity

Parents of protein-succinyllysine desuccinylase activity (GO:0036055)

subject	relation	object
protein-succinyllysine desuccinylase activity	RO:0000057	L-lysinium residue (CHEBI:29969)
protein-succinyllysine desuccinylase activity	RO:0000057	NAD(1-) (CHEBI:57540)
protein-succinyllysine desuccinylase activity	RO:0000057	nicotinamide (CHEBI:17154)
protein-succinyllysine desuccinylase activity	is_a	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811)
protein-succinyllysine desuccinylase activity	RO:0000057	water (CHEBI:15377)
protein-succinyllysine desuccinylase activity	RO:0000057	2''-O-succinyl-ADP-D-ribose(3-) (CHEBI:87832)
protein-succinyllysine desuccinylase activity	RO:0000057	N(6)-succinyl-L-lysine(1-) residue (CHEBI:87830)
protein-succinyllysine desuccinylase activity	BFO:0000050	peptidyl-lysine desuccinylation (GO:0036049)

This term has no children.

RHEA: 47668