class 1 mPTS binding, PEX19-dependent mPTS binding
Alternate IDs
None
Definition
Binding to a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner.
Source:
GOC:pm,
PMID:17020786,
PMID:14709540
Comment
Currently identified mPTSs vary greatly in length, and cannot be distinguished by primary structure analysis, suggesting that the peroxisomal sorting information is not contained within a specific amino acid sequence. There do however appear to be two classes of mPTSs: class 1 mPTSs that are bound by PEX19 and imported in a PEX19-dependent manner, and class 2 mPTSs that are not bound by PEX19 and mediate protein import independently of PEX19. The two classes cannot be defined based on their amino acid sequence.
Link
to all genes and gene products annotated to peroxisome membrane class-1 targeting sequence binding (excluding "regulates").
Link
to all direct and indirect annotations
to peroxisome membrane class-1 targeting sequence binding (excluding "regulates").
Link
to all direct and indirect annotations download (limited to first 10,000)
for peroxisome membrane class-1 targeting sequence binding (excluding "regulates").