AmiGO 2: Term Details for "prostaglandin H2 endoperoxidase reductase activity" (GO:0036130)

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Term Information

Accession: GO:0036130
Name: prostaglandin H2 endoperoxidase reductase activity
Ontology: molecular_function
Synonyms: PGH2 9,11-endoperoxidase, PGH2 9-,11-endoperoxide reductase
Alternate IDs: None
Definition: Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate). Source: PMID:16475787, PMID:10622721, PMID:14979715, GOC:mw, KEGG_REACTION:R02264
Comment: None
History: See term history for GO:0036130 at QuickGO
Chem. react.: has participant NADPH(4-); has participant prostaglandin F2alpha(1-); has participant NADP(3-); has participant hydron; has participant prostaglandin H2(1-)
Subset: None
Related: Link to all genes and gene products annotated to prostaglandin H2 endoperoxidase reductase activity (excluding "regulates").; Link to all direct and indirect annotations to prostaglandin H2 endoperoxidase reductase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for prostaglandin H2 endoperoxidase reductase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0044237 cellular metabolic process
GO:0009987 cellular process
GO:0071704 organic substance metabolic process
GO:0044238 primary metabolic process
GO:0044281 small molecule metabolic process
GO:0019752 carboxylic acid metabolic process
GO:0006629 lipid metabolic process
GO:0006082 organic acid metabolic process
GO:0044255 cellular lipid metabolic process
GO:0003674 molecular_function
GO:0032787 monocarboxylic acid metabolic process
GO:0043436 oxoacid metabolic process
GO:0003824 catalytic activity
GO:0006631 fatty acid metabolic process
GO:0006690 icosanoid metabolic process
GO:0016491 oxidoreductase activity
GO:0033559 unsaturated fatty acid metabolic process
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0006692 prostanoid metabolic process
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0006693 prostaglandin metabolic process
GO:0036130 prostaglandin H2 endoperoxidase reductase activity

Parents of prostaglandin H2 endoperoxidase reductase activity (GO:0036130)

subject	relation	object
prostaglandin H2 endoperoxidase reductase activity	BFO:0000050	prostaglandin metabolic process (GO:0006693)
prostaglandin H2 endoperoxidase reductase activity	RO:0000057	NADPH(4-) (CHEBI:57783)
prostaglandin H2 endoperoxidase reductase activity	is_a	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
prostaglandin H2 endoperoxidase reductase activity	RO:0000057	prostaglandin F2alpha(1-) (CHEBI:57404)
prostaglandin H2 endoperoxidase reductase activity	RO:0000057	NADP(3-) (CHEBI:58349)
prostaglandin H2 endoperoxidase reductase activity	RO:0000057	hydron (CHEBI:15378)
prostaglandin H2 endoperoxidase reductase activity	RO:0002162	Eumetazoa (NCBITaxon:6072)
prostaglandin H2 endoperoxidase reductase activity	RO:0000057	prostaglandin H2(1-) (CHEBI:57405)

This term has no children.

KEGG_REACTION: R02264
Reactome: R-HSA-2161549
RHEA: 45312