Term Information

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Accession
GO:0036131
Name
prostaglandin D2 11-ketoreductase activity
Ontology
molecular_function
Synonyms
PGD2 11-ketoreductase, prostaglandin 11-keto reductase
Alternate IDs
None
Definition
Catalysis of the reaction: prostaglandin D2 + H+ + NADPH = 11-epi-prostaglandin F2alpha + NADP+. Source: KEGG_REACTION:R02799, EC:1.1.1.188, PMID:3862115, PMID:1504718, GOC:mw
Comment
None
History
See term history for GO:0036131 at QuickGO
Chem. react.
has participant NADP(3-)
has participant NADPH(4-)
has participant hydron
has participant 11-epi-prostaglandin F2alpha(1-)
has participant prostaglandin D2(1-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of prostaglandin D2 11-ketoreductase activity (GO:0036131)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
prostaglandin D2 11-ketoreductase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
prostaglandin D2 11-ketoreductase activity [RO:0000057 relation] RO:0000057  NADP(3-) (CHEBI:58349)
prostaglandin D2 11-ketoreductase activity [BFO:0000050 relation] BFO:0000050  prostaglandin metabolic process (GO:0006693)
prostaglandin D2 11-ketoreductase activity [RO:0000057 relation] RO:0000057  NADPH(4-) (CHEBI:57783)
prostaglandin D2 11-ketoreductase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
prostaglandin D2 11-ketoreductase activity [RO:0000057 relation] RO:0000057  11-epi-prostaglandin F2alpha(1-) (CHEBI:85173)
prostaglandin D2 11-ketoreductase activity [RO:0000057 relation] RO:0000057  prostaglandin D2(1-) (CHEBI:57406)

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EC
1.1.1.188
KEGG_REACTION
R02799
Reactome
R-HSA-2161614
RHEA
45316