Term Information

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Accession
GO:0036132
Name
13-prostaglandin reductase activity
Ontology
molecular_function
Synonyms
15-oxoprostaglandin 13-reductase activity, 15-ketoprostaglandin delta13-reductase activity, 15-oxo-delta13-prostaglandin reductase activity, delta13-15-ketoprostaglandin reductase activity, prostaglandin 13-reductase activity, prostaglandin delta13-reductase activity
Alternate IDs
None
Definition
Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin. Source: PMID:17449869, KEGG_REACTION:R04557, KEGG_REACTION:R04556, EC:1.3.1.48, GOC:mw
Comment
Note that this is the reverse of the reaction described in '15-oxoprostaglandin 13-oxidase activity ; GO:0047522'.
History
See term history for GO:0036132 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of 13-prostaglandin reductase activity (GO:0036132)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
13-prostaglandin reductase activity [BFO:0000050 relation] BFO:0000050  prostaglandin metabolic process (GO:0006693)
13-prostaglandin reductase activity [RO:0002162 relation] RO:0002162  Eumetazoa (NCBITaxon:6072)
13-prostaglandin reductase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)

This term has no children.

EC
1.3.1.48
KEGG_REACTION
R04557
R04556
Reactome
R-HSA-2161692